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Importantly, astrocytes obtained from various brain regions differ in their capacities to stimulate neuronal migration, survival, growth, and uptake of extracellular glutamate, aspects that are critical in the pathology of ALS [90, 97, 98]

Nearly all of the identified causal genes for Mendelian forms of human blood pressure abnormalities involve kidney function 7,8 , and most of the commonly used animal models of hypertension present kidney abnormalities 9

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